[elmariachi]

I don't have much experience with 2x4s beyond the original medium riser set I have (Holley list 3300/list 3301, also known as the BC/BD set). I love them, and I believe Ford must have spent a lot of time selecting their carbs for these engines. Though these are based on the 4160, they don't seem to have many common parts to other models.

I have had great luck running the original setup so if it were me, I'd buy a set of the original Holley BJ/BK reproduction low-riser carbs tuned for your intake from Carl's Ford Parts. The original linkage is available from Greg Donohue Restorations. They are very straight-forward to setup and tune and are very street able. Also, lots of good info on this subject over on the FE forum.