[Toivo]

Strokers are great idea's.
You need to worry about the compression height issues though...a stroker's piston is necessarily shorter in order to fit and this leads to ring land issues. Also, because the piston is shorter it tends to rock in the bore more.
Other than that, I can't think of anything bad about stroker motors. Even the 'won't rev' claim is relatively moot nowadays. The only thing you need to keep in mind is that if you go to a 427 stroker, that thing will need a lot more air than a 302 or 347 so you need to allow for that with the head and cam selections.
It is also way cheaper to build than a 427SO nowadays and you have a far wider selection of parts and places familiar with them.