I think I understand what your after as your are considering a transplant or crate motor. Also not trying to pitch the intake and injector system the comes on the engines.
In which case you only need the XFI interface and controller.
http://www.fuelairspark.com/fas/xfi-...yote-5-0lhtml/
http://www.fuelairspark.com/fas/xfit...6-currenthtml/
These to do come with several tables pre-installed and user selectable and just like the Holley/Atomic/FiTech and will self tune to some extent. Fine tuning on a dyno can be complied with but usually not required unless you want to eek out some extra HP.
Some folks feel EFI daunting and can spout a lot of rhetoric and "I've read this on a forum".
Personally I love Self learning EFI as I have an FiTech and won't go back to the Holley 4150HP at least on this car. I'm not qualified to judge the merits or failing of systems I don't own or have not worked on.
I'd check out the FAST forums and you will probably get the best 1st hand feedback there from real users.
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