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if u tune the neigne with throttle sensor then i think u leave it unplugged
and it is then used as a barometric sensor

if u run a boosted engine u need it connected to measure boost and u then tune the enigne using vacuum/boost

if u have multiple throttle bodies and boost u then tune it using throttle up untill 0vac/0boost then once u go onto boost u tune it using the vac sensor or map sensor as its called

i think they will tune yr enigne using throttle as its a tad more prescise when its non boosted when compared to using the map sensor
so maybe leave it off but check with yr tuner he might want it connected so he can measure vacuum

weve starte dplaying with ls1 ecus more these days
see what else we can fit them too
plus we are making ls1 dual tune ecus
should be a good thing flick a switch and u go from std tune to a performance tune