Henry Olsen (working with John Bishop) has done much research and written quite a bit about carb/ignition tuning. Henry is the author in links that Tom posted above. Here's another link to Henry's work tuning a Roush 427 in a Brizzio Hot Rod:
http://automotiveu.com/tuningperformance.htm
For those in the SF Bay Area, Henry is available on Saturdays (by appointment) to fully tune 4 cars per Saturday. His contact information is in the links... I highly recommend him!