Kaspersky is good, and so is CA eTrust. I use AVG Ant-virus. Other programs I use include Spy Bot, Ad Aware,and Malwarebytes for spy and malware. I use CCleaner to clean off unneeded files and to fix some registry issues.
Over 90% of the machines I have to deal with have some kind of issue with spy and malware.
Every thing I use can be found at
www.filehippo.com.
Good luck.