I retired from the dyno tuning scene in June 04. Many reasons, none of them bad...just time to focus on my career and enjoy some free building my blown cobra.
As far as dyno-tuning, here's my advice.
If the carb is easily jetted at the dyno, and assuming you're proficient at the task...or the dyno operator voulenteers and is proficient at the task, that's a fine option. A few hours or dyno time (2-4), you can dial it in.
If the carb is not easily jetted on the dyno, pull it off and send it to a CARB DYNO service. Essentially, they put your carburetor on a test engine at their facility and tune it. Some use V8 engines, some use air pumps and ignitors. The Carb Shoppe in the LA area does excellent work. You'll have the carb back in a week or so, and it'll be right. Bolt it on the engine, the proceed to the dyno for a quick pull to see the air/fuel ratio under load. I've done this numerous times with singles, duals, and even blow-through supercharged combinations and it is a fantastic effortless option.
Or, for the DIY enthusiast that wants the biggest bang for the buck, buy yourself a UEGO wideband system like the Innovate.
http://www.innovatemotorsports.com
For $400 you'll enjoy seeing real-time Air/Fuel accurately and will have the ability to tune AFR on the street/strip without a dyno. And lastly, you'll be able to watch that Air/Fuel ratio and know precisely when fueling problems raise their ugly head...before damage is done.
Or you can go psycho like me and convert it all to EFI.
Byron